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Year : 2018  |  Volume : 1  |  Issue : 1  |  Page : 1-4

Diagnostic issue and caveats of immunoreactivity for Ki67 in hyalinizing trabecular neoplasm with review of literature: A study of one case

1 Department of Pathology, L.L.R.M. Medical College, Meerut, Uttar Pradesh, India
2 Department of Pathology, Subharti Medical College, Meerut, Uttar Pradesh, India

Correspondence Address:
Veer Karuna
Department of Pathology, L.L.R.M. Medical College, Meerut, Uttar Pradesh
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Source of Support: None, Conflict of Interest: None

DOI: 10.4103/JHNP.JHNP_6_18

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Few benign and malignant thyroid lesions share many histological features including papillary and trabecular pattern, hyalinized stroma, calcification, nuclear grooving and nuclear inclusion. Well formalin fixed right lobe hemithyroidectomy specimen was received. After processing, H and E stain was done. Immunohistochemical studies (TTF, Thyroglobuline, MIB-1) and special stain (Congo red) were done to make a definite diagnosis. The present case describes a relatively rare thyroid tumour – Hyalinizing trabecular tumour with its varied morphological features creating diagnostic difficulties and role of IHC in formulating definitive diagnosis.

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