RT - Journal TY - JOUR A1 - Narla, Swetha A1 - Pande, Anil A1 - Pande, Meenakshi A1 - Subramanyan, Annapurneswari T1 - Von Hippel–Lindau disease with renal cell carcinoma and multiple cerebellar and spinal hemangioblastomas without retinal manifestations: A case report YR - 2020/7/1 JF - International Journal of Head and Neck Pathology JO - Int J Head Neck Pathol SP - 27 OP - 31 VO - 3 IS - 2 UL - https://www.ijhnp.org/article.asp?issn=2590-2997;year=2020;volume=3;issue=2;spage=27;epage=31;aulast=Narla;t=5 DO - 10.4103/JHNP.JHNP_12_21 N2 - A 35-year-old gentleman presented with headache in the occipital region, neck pain, slurring of speech, and vomiting. There was reported history of Von Hippel–Lindau disease (VHL) in his mother, who was operated for a cerebellar hemangioblastoma. On investigations, magnetic resonance imaging brain showed bilateral cerebellar hemangioblastomas and a tiny spinal hemangioblastoma. Contrast-enhanced computed tomography abdomen showed multiple small well-defined, non-enhancing hypodense lesions with fluid attenuation in the left kidney and pancreas, suggestive of simple cysts. There was history of right partial nephrectomy in the past for renal cell carcinoma. Complete excision of bilateral cerebellar hemangioblastomas was performed. Histopathological examination and immunohistochemical workup confirmed the clinical diagnosis of hemangioblastoma. ER -